Zhen Zhang received her B. S. degree in Chemistry from Wuhan University in 2004 and obtained her Ph. D. degree in Chemistry Biology from Peking University in 2009. After that, she worked as a postdoctoral researcher at Prof. Xiaohong Fang’s group. Now, she works as a research associate at this group. Her present research interests in developing aptamer-based disease related protein detection assay and researching on new ultrasensitive visual methods based on nanoparticle catalysis property.

Publications：

1.         Zhen Zhang, Zilong Zhao, Li Xu, Xinjiao Wu, Haizhen Zhu, Weihong Tan and Xiaohong Fang,” Hepatitis C virus core protein detection by DNA aptamer”, Sci China Ser B-Chem, 2011, 41, 1312.

2.         Zhen Zhang, Chunlai Chen, and Xin Sheng Zhao, “A simple and sensitive biosensor based on silver enhancement of aptamer-gold nanoparticle aggregation”, Electroanalysis, 2009, 21, 1316.

3.         Li Xu, Zhen Zhang, Zilong Zhao, Qiaoling Liu, Weihong Tan, Xiaohong Fang, “Cellular Internalization and Cytotoxicity of Aptamers Selected from Lung Cancer Cell”, Am. J. Biomed. Sci. 2013, 5, 47.

4.         Qlinglin Shen, Li Xu, Libo Zhao, Dongxia Wu, Yunshan Fan, iliang Zhou, Wei-Han OuYang， Xiaochun Xu, Zhen Zhang, Tom Lee, Bin Xiong, Shuang Hou, Hsian-Rong Tseng, Xiaohong Fang, “Specific capture and release of circulating tumor cells using aptamer modified nanosubstrates”, Adv. Mater., 2013, 25, 2368.

5.         Jiajing Zhang, Zhen Zhang, Xin Nie, Zhenjiang Zhang, Xiaochun Wu, Chunying Chen, Xiaohong Fang, “A Label-Free Gold Nanocluster Fluorescent Probe for Protease Activity Monitoring”, J. Nanosci. Nanotechnol. 2013, Accepted.

6.         Mianqi Xue, Zhen Zhang, Nan Zhu, Fangfang Wang, Xin Sheng Zhao, and Tingbing Cao，“Transfer printing of metal nanoparticles with controllable dimensions, placement and reproducible SERS effects”, Langmuir, 2009, 25, 4347.

7.         Zhaoqiang Wu, Shuling Gong, Cheng Li, Zhen Zhang, Weihua Huang, Lingzhi Meng, Xiaoju Lu, Yongbing He, “Novel water-soluble fluorescent polymer containing recognition units: synthesis and interactions with PC12 cell”, European Polymer Journal, 2005, 41, 1985.

8.         Wei-Hua Huang, Wei Cheng, Zhen Zhang, Dai-Wen Pang, Zong-Li Wang, Jie-Ke Cheng, Da-Fu Cui, “Transport, location, and quantal release monitoring of single cells on a microfluidic devive”, Anal. Chem., 2004, 76, 483.

Patents：

1.         Xiaohong Fang，Zhen Zhang，Zilong Zhao，Li xu，Haizhen Zhu，Hepatitis C virus core protein binding aptamers and their applications, 201010581008.3.

2.         Xiaohong Fang, Jiajing Zhang, Zhen Zhang, Chunying Chen, A method for chymotrypsin activity monitoring by gold nanocluster, 201310136872.6.