Members---Chinese Academy of Sciences Key Laboratory of Molecular Nanostructure and Nanotechnology

Li Xu received her B.S. degree in life science from Liaoning Normal University in 1996 and Ph.D degree in physiology from institute of zoology, CAS in 2006. Her present research interests in mainly on: 1. The aptamer selection from cell, tissue and protein; 2. Aptamer function in vitro and in vivo.

1. Shen QL, Xu L, Zhao LB, Wu DX, Fan YS, Zhou IL, Ouyang WH, Xu XC, Zhang Z, Lee T, Xiong B*, Hou S*, Tseng HR*, Fang XH*. Specific capture and release of circulating tumor cells using aptamer modified nanosubstrates. Advanced Materials, 2013, 25(16): 2368-2373.（co-first author）

2. Liu QL, Xu L, Zhang XJ, Li N, Zheng JP, Guan MR Fang XH*, Wang CR* ; Shu CY*. Enhanced photodynamic efficiency of an aptamer-guided fullerene photosensitizer toward tumor cells, Chemisrty-An Asian Journal, 2013, in press, DOI: 10.1002/asia.201300039. （co-first author）

3. Xu L, Zhang Z, Zhao ZL, Liu QL, Tan WH, Fang XH*. Cellular internalization and cytotoxicity of aptamers selected from lung cancer cell. American Journal of Biomedical Sciences, 2013, 5: 47-58.

4. Wei YJ, Zhang XJ, Xu L, Yi SQ, Li Y, Fang XH, Liu HL*. The effect of cigarette smoke extract on thrombomodulin-thrombin binding: an atomic force microscopy study. SCINECE CHINA: Life Sciences, 2012, 55: 891-897.

5. Liu QL, Guan MR, Xu L, Shu CY*, Zheng JP, Fang XH*, Yang YJ, and Wang CR*. The structural effect and mechanism study of C70-carboxyl-fullerenes as an efficient sensitizer against cancer cells. Small, 2012, 8: 2070-2077.

6. Hepatitis C virus core protein detection by DNA aptamer, Zhang, Z.; Zhao, Z.; Xu, L.; Wu, X.; Zhu, H.; Tan, W.; Fang, X. * Scientia Sinica Chimica, 2011, 41 (8): 1312-1318

7. Zhao ZL, Xu L, Shi XL, Tan WH, Fang XH*, Dihua SG. Recognition of subtype non-small cell lung cancer by DNA aptamer selected from living cells. Analyst, 2009, 134: 1808-1814.

8. Shi XL, Xu L, Yu JP, Fang XH*. Study of inhibition effect of herceptin on interaction between heregulin and ErbB receptors HER3/HER2 by single-molecule force spectroscopy. Experimental cell research, 2009, 315: 2847-2855.