Chunying Shu
Ph. D., Professor of Chemistry
Key Laboratory of Molecular Nanostructure and Nanotechnology
Institute of Chemistry
The Chinese Academy of Sciences (CAS)
Beijing 100190, P. R. China
Tel/Fax: 010-62554473
E－mail: shucy@iccas.ac.cn
Biography:
Dr. Chunying Shu is a Professor of Chemistry at the Institute of Chemistry (ICCAS), the Chinese Academy of Sciences (CAS) in Beijing.
She was born in 1974, Shandong Province. She received her Ph.D. degree in Physical Chemistry from CAS in 2006. From 2006 to 2009 she worked in Chemistry Department of Virginia Polytechnic Institute and State University (USA) and School of Medicine, Virginia Commonwealth University. In 2009, she was awarded the “Distinguished Young Scholar of ICCAS” and appointed research Professor at the ICCAS, joined the CAS Key Laboratory of Molecular Nanostructure and Nanotechnology. Since 2013, she was appointed as a Director of Division of Personnel and Education, ICCAS.
In recent years, Dr. Shu authored/co-authored more than 40 scientific papers in refereed journals (JACS, Angew. Chem. Int. Ed., Bioconjugate Chem., Chem. Mater., Org. Lett., CrystEngComm etc.). Her major research field includes Nano Biomedicine; Biomedical Materials; and Materials Chemistry based on carbonaceous nanomaterials, including fullerenes, endofullerenes, carbon nanotubes/horns, graphene and so on.
Research Interests:
The research is devoted to 1) imaging of nano-biomaterials, including tissue-targeting and high efficient MRI contrast agent, multimodality molecular imaging probes for the accurate diagnosis of disease, and radiolabelled probes for biodistribution study of nanomaterials; 2) multifunctional nanomaterials for the theranostics of diseases, including the application of functional carbonaceous nanomaterials in PDT and PTT, and drug-deliver system for targeting imaging and therapy.
Publications:
2013
1. Ruimin Li, Mingming Zhen, Mirong Guan, Daiqin Chen, Guoqiang Zhang, Jiechao Ge, Ping Gong, Chunru Wang, Chunying Shu* A novel glucose colorimetric sensor based on intrinsic peroxidase-like activity of C60-carboxyfullerenes. Biosensors and Bioelectronics, 2013, 47, 502–507.
2. Feng Jiang, Daiqin Chen, Ruimin Li, Yucheng Wang, Guoqiang Zhang, Shumu Li, Junpeng Zheng, Naiyan Huang, Ying Gu, Chunru Wang and Chunying Shu* Eco-friendly synthesis of size-controllable aminefunctionalized graphene quantum dots with antimycoplasma properties. Nanoscale, 2013, 5, 1137–1142.
2012
3. Junpeng Zheng, Qiaoling Liu, Mingming Zhen, Feng Jiang, Chunying Shu,* Chan Jin, Yongji Yang, H. A. Alhadlaqd, and Chunru Wang* Multifunctional imaging probe based on gadofulleride nanoplatform. Nanoscale, 2012,4 (12), 3669 - 3672.
4. Qiaoling Liu, Mirong Guan, Li Xu, Chunying Shu,* Chan Jin, Junpeng Zheng, Xiaohong Fang,* Yongji Yang, Chunru Wang* The Structural Effect and Mechanism Study of C70-carboxylfullerenes as an Efficient Sensitizer against Cancer Cells, Small, 2012,8(13):2070-7.
5. Mingming Zhen, Junpeng Zheng, Lei Ye, Shumu Li, Chan Jin, Kai Li, Dong Qiu, Hongbin Han, Chunying Shu,* Yongji Yang, and Chunru Wang* Maximizing the Relaxivity of Gd-Complex by Synergistic Effect of HSA and Carboxylfullerene. ACS Applied Materials & Interfaces 2012, 4 (7), 3724–3729.
6. Chunying Shu and Chunru Wang. Chapter 5.3 MRI contrast agent based on metallofullerenes in Biomedical Imaging (p261-281)-The Chemistry of Labels, Probes and Contrast Agent, Edited by Martin Braddock, RSC Drug Discovery Series No. 15, Royal Society of Chemistry 2012.
7. Junping Yu, Mirong Guan, Fengyun Li, Zhiping Zhang, Chunru Wang, Chunying Shu,* Hongping Wei* and Xian-En Zhang.* Effects of fullerene derivatives on bioluminescence and application for protease detection. Chem. Commun., 2012, 48, 11011–11013.
8. Xiangyue Meng, Wenqing Zhang, Zhan'ao Tan, Chun Du, Cuihong Li, Zhishan Bo, Yongfang Li,* Xiulin Yang, Mingming Zhen, Feng Jiang, Junpeng Zheng, Taishan Wang, Li Jiang, Chunying Shu* and Chunru Wang*. Dihydronaphthyl-based [60]fullerene bisadducts for efficient and stable polymer solar cells. Chem. Commun. 2012, 48, 425–427.
9. Xiangyue Meng, Wenqing Zhang, Zhan'ao Tan,* Yongfang Li, Yihan Ma, Taishan Wang, Li Jiang, Chunying Shu and Chunru Wang*. Highly Efficient and Thermally Stable Polymer Solar Cells with Dihydronaphthyl-Based [70]Fullerene Bisadduct Derivative as the Acceptor. Adv. Funct. Mater. 2012, 22: 2187-2193. (IF=10.179)
10. Li Xu, Shu-Fei Li, Li-Hua Gan*, Chun-Ying Shu, Chun-Ru Wang*. The structures of trimetallic nitride fullerenes M3N@C88: Theoretical evidence of corporation between electron transfer interaction and size effect. Chemical Physics Letters, 2012, 521, 81-85.
11. Taishan Wang , Jingyi Wu , Yongqiang Feng , Yihan Ma , Li Jiang , Chunying Shu and Chunru Wang. Preparation and ESR study of Sc3C2@C80 bis-addition fulleropyrrolidines. Dalton Trans., 2012, 41, 2567-2570.
12. Yihan Ma, Taishan Wang*, Jingyi Wu, Yongqiang Feng, Wei Xu, Li Jiang, Junpeng Zheng, Chunying Shu and Chunru Wang*, Susceptible electron spin adhering to an yttrium cluster inside anazafullerene C79N. Chem. Commun., 2012, 48, 11570-11572.
13. Xiulin Yang, Junpeng Zheng, Mingming Zhen, Xiangyue Meng, Feng Jiang, Taishan Wang, Chunying Shu, Li Jiang,* Chunru Wang.* A linear molecule functionalized multi-walled carbon nanotubes with well dispersed PtRu nanoparticles for ethanol electro-oxidation. Applied Catalysis B: Environmental 2012, 121-122, 57-64.
14. Jing-yi Wu, Wei Xu, Tai-Shan Wang, Li Jiang, Chun-Ying Shu, and Chun-Ru Wang. A density functional theory investigation for the open-shell metal-carbide endofullerene Lu3C2@C88(D2:35) and closed-shell metal-nitride endofullerene Lu3N@C88(D2:35). J Nanosci Nanotechnol. 2012,12(3):2254-2260.
15. Xiulin Yang, Xueyun Wang, Guoqiang Zhang, Junpeng Zheng, Taishan Wang, Xianzong Liu, Chunying Shu, Li Jiang*, Chunru Wang*. Enhanced electrocatalytic performance for methanol oxidation of Pt nanoparticles on Mn3O4-modified multi-walled carbon nanotubes. International Journal of Hydrogen energy. 2012, 37, 11167-11175.
16. Hui Li, Taishan Wang, Yanjun Zhang, Li Jiang, Chunying Shu*, and Chunru Wang*. Controllable Fabrication of Iron Oxide/Oxyhydroxide with Diverse Nanostructures and Their Excellent Performance in Visible Light Induced Photocatalytic Degradation of Rhodamine B. J. Nanosci. Nanotechnol. 2012, 12(3), 1910-1918.
17. Jingyi Wu, Taishan Wang, Chunying Shu, Xin Lv, Chunru Wang. Identification of the most stable Sc2C80 Isomers: Structure Electronic Property, and Molecular Spectra Investigations. Chin. J. Chem. 2012, 30, 765—770.
18. Li-Hua Gan, Qing Chang, Li Xu, Xing-Liang Huang, Chun-Ying Shu, Chun-Ru Wang. An anti-aromatic isomer of fullerene C60 violating the pentagon adjacent penalty rule. Chemical Physics Letters, 2012, 532, 68-71.
19. Yanxia Ji, Ziyu Rao, Jinlei Cui, Haiying Bao, Chunying Chen, Chunying Shu, Jian Ru Gong. Ginsenosides Extracted from Nanoscale Chinese White Ginseng Enhances Anticancer Effect. Journal of Nanoscience and Nanotechnology, 2012,12 (8), 6163-6167(5).
20. Yuhong Liu*, XiaoKang Wang, PengXiao Liu, JunPeng Zheng, ChunYing Shu, GuoShun Pan and JianBin Luo. Modification on the tribological properties of ceramics lubricated by water using fullerenol as a lubricating additive. Science China, 2012, 55(9), 2656-2661.
2011
21. Jing-yi Wu, Tai-shan Wang, Yi-han Ma, Li Jiang, Chun-ying Shu, and Chun-ru Wang. Synthesis, Isolation, Characterization, and Theoretical Studies of Sc3NC@C78-C2. J. Phys. Chem. C. 2011, 115(48), 23755-23759.
22. Fillmore, H. L.; Shultz, M. D.; Henderson, S. C.; Cooper, P.; Broaddus, W. C.; Chen, Z. J.; Shu, C. Y.; Zhang, J. F.; Ge, J. C.; Dorn, H. C.; Corwin, F.; Hirsch, J. I.; Wilson, J.; Fatouros, P. P.Conjugation of functionalized gadolinium metallofullerenes with IL-13 peptides for targeting and imaging glial tumors Nanomedicine-Uk 2011, 6, 449-458.
23. Li, H.; Li, W.; Zhang, Y.; Wang,T.; Jiang, L.; Song,W.; Shu, C.;* and Wang, C.* Chrysanthemum-like α-FeOOH microspheres produced by a simple green method and its excellent performance in heavy metal removal. J. Mater. Chem. 2011, 21(22), 7878-7881.
24. 蒋礼, 王太山, 舒春英, 王春儒* 内嵌富勒烯的研究进展.中国科学2011, 41(4), 629- 644.
25. Zhang, Y. J.; Li, H.; Jiang, L.;Liu, H. B.;Shu, C. Y.;*Li, Y. L.;Wang, C. R.* Field emission from GeSe2 nanowalls. Appl. Phys. Lett. 2011, 98, 113118(1-3).
26. Xu, W.; Feng, L.; Wu,Y.S.; Wang, T. S.; Wu, J. Y.; Xiang, J. F.; Li, B.; Jiang, L.; Shu, C. Y.* and Wang, C. R.* Construction and photophysics study of supramolecular complexes composed of three-point binding fullerene-trispyridylporphyrin dyads and zinc porphyrin. Phys. Chem. Chem. Phys., 2011, 1463-9076.
27. Xu, W.; Wang, T. S.; Wu, J. Y.; Ma, Y. H.; Zheng, J. P.; Li, H.; Wang, B.; Jiang, L.; Shu, C. Y.* and Wang, C. R.* Entrapped Planar Trimetallic-Carbide in a Fullerene Cage: Synthesis, Isolation, and Spectroscopic Studies of Lu3C2@C88. J. Phys. Chem. C, 2011, 115 (2), 402–405.
28. Yihan Ma, Taishan Wang, Jingyi Wu, Yongqiang Feng, Wei Xu, Li Jiang, Junpeng Zheng, Chunying Shu and Chunru Wang. Size effect of endohedral cluster on fullerene cage: Preparation and structural studies of Y3N@C78-C2. Nanoscale, 2011, 3, 4955-4957.
2010
29. Zhang, Y. J.; Wang, J. J.; Zhu, H. F.; Li, H.; Jiang, L.; Shu, C. Y.*; Hu, W. P.; Wang, C. R.* High performance ultraviolet photodetectors based on an individual Zn2SnO4 single crystalline nanowire. J. Mater. Chem., 2010, 20, 9858-9860.
30. Wang, T. S.; Feng, L.; Wu, J. Y.; Xu, W.; Xiang, J. F.; Tan, K.; Ma, Y. H.; Zheng, J. P.; Jiang, L.; Lu, X.; Shu, C. Y.* and Wang, C. R.* Planar Quinary-Cluster inside a Fullerene Cage: Synthesis and Structural Characterizations of Sc3NC@C80-Ih. J. Am. Chem. Soc., 2010, 132 (46), 16362–16364.
31. Wang, B.; Shu, C. Y.; Wang, C. R.* Metal-free preparation of multi-walled carbon nanotubes based on new-diamond-induced growth mechanism. J. Mater. Chem., 2010, 20, 7104-7106.
32. Wang, B.; Wu, X. L.; Shu, C. Y.; Guo, Y. G.; Wang, C. R.* Synthesis of CuO/graphene nanocomposite as a high-performance anode. J. Mater. Chem., 2010, 20, 10661-10664.
33. Zhang, J. F.; Ge, J.; Shultz, M. D.; Chung, E.; Singh, G.; Shu, C.Y. et al. In Vitro and in Vivo Studies of Single-Walled Carbon Nanohorns with Encapsulated Metallofullerenes and Exohedrally Functionalized Quantum Dots.Nano lett. 2010, 10 (8), 2843–2848.
34. Zhang, J. F.; Fatouros, P. P.; Shu, C. Y.; Reid, J.; Owens, L. S.; Cai, T.; Gibson, H. W.; Long, G. L.; Corwin, F. D.; Chen Z.-J. and Dorn, H. C. High Relaxivity Trimetallic Nitride (Gd3N) Metallofullerene MRI Contrast Agents with Optimized Functionality. Bioconjugate Chem., 2010, 21 (4), 610–615.
35. Shultz, M. D.; Duchamp, J. C.; Wilson, J. D.; Shu, C.Y.; Ge, J.; Zhang, J.; Gibson, H. W.; Fillmore, H. L.; Hirsch, J. I.; Dorn, H. C.; Fatouros, P. P. Encapsulation of a radiolabeled cluster inside a fullerene cage, 177LuxLu3-xN@C80: an interleukin-13-conjugated radiolabeled metallofullerene platform. J. Am. Chem. Soc., 2010, 132, 4980-1.
36. Burke, B.G.; Chan, J.; Williams, K.A.; Ge, J. C.; Shu, C.Y.; Fu, W.J.; Dorn, H.C.; Kushmerick, J.G.; Puretzky, A.A.; Geohegan, D.B. Investigation of Gd3N@C2n (40 < n < 44) family by Raman and inelastic electron tunneling spectroscopy. Physical Review B 2010, 81, 115423(1-7).
37. Wang, T.S.; Wu, J.Y.; Xu, W.; Xiang, J.F.; Lu, X.; Li, B.; Jiang, L.; Shu, C.Y.*; Wang, C.R.* Spin Divergence Induced by Exohedral Modification: EPR Study of Sc3C2@C80 Fulleropyrrolidine. Angew. Chem., Int. Ed. 2010, 49, 1786-1789.
38. Li, B.; Shu, C.Y.;* Lu, X.;* Dunsch, L.; Chen, Z.F.; Dennis, T.J.S.; Shi, Z.Q.; Jiang, L.; Wang, T.S.; Xu, W.; Wang, C.R.* Addition of Carbene to the Equator C70 To Produce the Most Stable C71H2 Isomer: 2aH-2(12)a-Homo(C-70-D-5h(6))[5,6]fullerene. Angew. Chem. Int. Ed. 2010, 49, 962-966.
39. Shu, C.Y.; Zhang, J.F.; Ge, J.C.; Sim, J.H.; Burke, B.G.; Williams, K.A.; Rylander, W.M.; Campbell, T.; Puretzky, A.; Rouleau, C.; Geohegan, D.B.; More, K.; Esker, A.R.; Gibson, H.W.; Dorn, H.C. A Facile High-speed Vibration Milling Method to Water-disperse Single-walled Carbon Nanohorns. Chem. Mater. 2010, 22, 347-351.
2009
40. Wang, T. S.; Chen, N.; Xiang, J. F.; Li, B.; Wu, J. Y.; Xu, W.; Jiang, L.; Tan, K.; Shu, C.Y.*; Lu, X.*; Wang, C.R.* Russian-Doll-Type Metal Carbide Endofullerene: Synthesis, Isolation, and Characterization of Sc4C2@C80. J. Am. Chem. Soc. 2009, 131, 16646-16647.
41. Shu, C.Y.; Corwin, F.D.; Zhang, J.F.; Chen, Z.J.; Reid, J.E.; Sun, M.H.; Xu, W.; Sim, J.H.; Wang, C.R.; Fatouros, P.P.; Esker, A.R.; Gibson, H.W. and Dorn, H.C. Facile Preparation of a New Gadofullerene-Based Magnetic Resonance Imaging Contrast Agent with High 1H Relaxivity. Bioconjugate Chem, 2009, 20, 1186-1193.
42. Shu, C.Y.; Xu, W.; Slebodnick, C.; Champion, H.; Fu, W.J.; Reid, J.E.; Azurmendi, H.; Wang, C.R.; Harich, K.; Dorn, H.C. and Gibson, H.W. Syntheses and Structures of Phenyl-C81-Butyric Acid Methyl Esters (PCBMs) from M3N@C80 Metallofullerenes. Org. Lett. 2009, 11(8), 1753-1756.
43. Fu, W. J.; Xu, L. S.; Azurmendi, H.; Ge, J. C.; Fuhrer, T.; Zuo, T. M.; Reid, J.; Shu, C. Y.; Harich, K.; Dorn, H. C. Y-89 and C-13 NMR Cluster and Carbon Cage Studies of an Yttrium Metallofullerene Family, Y3N@C2n (n=40-43). J. Am. Chem. Soc. 2009, 131, 11762-11769.
44. Koppolu, V. R.; Gupta, M.C.; Bagienski, W.; Shen, Y.; Shu, C.Y.; Gibson, H.W.; Dorn, H.C. A Novel Solution Processable Electron Acceptor, C60(CN)2, for Bulk Heterojunction Photovoltaic Applications. Materials Research Society Symposium Proceedings, 2009, 1123, 165-170.
45. Koppolu, V. R.; Gupta, M.C.; Bagienski, W.; Shen, Y.; Shu, C.Y.; Gibson, H.W.; Dorn, H.C. Organic Solar Cells with a Blend of Two Solution Processable Electron Acceptors, C60(CN)2 and PCBM. IEEE Photovoltaic Specialists Conference, 2009, 798-803.
2008
46. Shu, C.Y.; Slebodnick, C.; Xu, L.S.; Champion, H.; Fuhrer, T.; Cai, T.; Reid, J.; Fu, W.J.; Harich, K.; Dorn, H.C. and Gibson, H.W. Highly Regioselective Derivatization of Trimetallic Nitride Endohedral Metallofullerenes via a Facile Photochemical Reaction. J. Am. Chem. Soc. 2008, 130 (52), 17755–17760.
47. Shu, C.Y.; Ma, X.Y.; Zhang, J.F.; Corwin, F.D.; Sim, J.H.; Zhang, E.Y.; Dorn, H.C.; Gibson, H.W.; Fatouros, P.P.; Wang, C.R. and Fang, X.H. Conjugation of a Water-Soluble Gadolinium Endohedral Fulleride with an Antibody as a Magnetic Resonance Imaging Contrast Agent. Bioconjugate Chem. 2008, 19, 651–655.
48. Shu, C.Y., Wang, C.R.; Zhang, J.F.; Gibson, H.W.; Dorn, H.C.; Corwin, F.D.; Fatouros, P.P. and Dennis, T.J.S. Organophosphonate Functionalized Gd@C82 as a Magnetic Resonance Imaging Contrast Agent. Chem. Mater. 2008, 20, 2106–2109.
49. Cai, T.; Xu, L.S.; Shu, C.Y.; Reid, J.E.; Gibson, H.W. and Dorn, H.C. Synthesis and Characterization of a Non-IPR Fullerene Derivative: Sc3N@C68[C(COOC2H5)2]. J. Phys. Chem. C 2008, 112 (49), 19203–19208.
50. Zuo, T.; Olmstead, M. M.; Beavers, C. M.; Balch, A. L.; Wang, G.; Yee, G. T.; Shu, C.; Xu, L.; Elliott, B.; Echegoyen, L.; Duchamp, J. C. and Dorn, H. C. Preparation and Structural Characterization of the Ih and the D5h Isomers of the Endohedral Fullerenes Tm3N@C80: Icosahedral C80 Cage Encapsulation of a Trimetallic Nitride Magnetic Cluster with Three Uncoupled Tm3+ Ions. Inorg. Chem. 2008, 47(12), 5234–5244.
2007
51. Shu, C.Y.; Cai, T.; Xu, L.S.; Zuo, T.M.; Reid, J.; Harich, K.; Dorn, H.C. and Gibson, H.W. Manganese (III) Catalyzed Free Radical Reactions on Trimetallic Nitride Endohedral Metallofullerenes. J. Am. Chem. Soc. 2007, 129(50), 15710–15717.
52. Zhang, X.F.; Shu, C.Y.; Xie, L.; Wang, C.R.; Zhang, Y.Z.; Xiang, J.F.; Li, L. and Tang, Y.L. Protein Conformation Changes Induced by a Novel Organophosphate-Containing Water-Soluble Derivative of a C60 Fullerene Nanoparticle. J. Phys. Chem. C 2007, 111, 14327–14333.
53. Zhang, E.Y.; Shu, C.Y.; Feng, L. and Wang, C.R.* Preparation and Characterization of Two New Water-Soluble Endohedral Metallofullerenes as Magnetic Resonance Imaging Contrast Agents. J. Phys. Chem. B2007, 111(51), 14223–14226.
54. Cai, T.; Xu, L.S.; Shu, C.Y.; Champion, H.A.; Reid, J.E.; Anklin, C.; Anderson, M.R.; Gibson, H.W. and Dorn, H.C.Selective Formation of a Symmetric Sc3N@C78 Bisadduct: Multi-Adduct Docking Controlled by an Internal Trimetallic Nitride Cluster. J. Am. Chem. Soc. 2007, 130(7), 2136–2137.
55. Chen, N.; Fan, L.Z.; Tan, K.; Wu, Y.Q.; Shu, C.Y.; Lu, X.* and Wang, C.R.* Comparative Spectroscopic and Reactivity Studies of Sc3-xYxN@C80 (x= 0-3). J. Phys. Chem. C 2007, 111, 11823–11828.
2006-2005
56. Shu, C.Y.; Zhang, E.Y.; Xiang, J.F.; Zhu, C.F.; Wang, C.R.* Pei, X.L. and Han, H.B. Aggregation Studies of the Water-Soluble Gadofullerene Magnetic Resonance Imaging Contrast Agent: [Gd@C82O6(OH)16(NHCH2CH2COOH)8]x. J. Phys. Chem. B 2006, 110, 15597-15601.
57. Shu, C.Y.; Gan, L.H.; Wang, C.R.; Pei, X.L. and Han, H.B. Synthesis and Characterization of a New Water-soluble Endohedral Metallofullerene for MRI Contrast Agents” Carbon, 2006, 44, 496–500.
58. Gan, L.H.; Shu, C.Y. andWang, C.R.* Chem. J. Chinese U., 2006, 27(6), 1106–1108.
59. Zeng, Q.D.; Wu, D.X.; Ma, H.W.; Shu, C.Y.; Li, Y. and Wang, C. Polymeric hydrogen-bonded supramolecules by self assembling of adamantane derivatives with bipyridines.CrystEngComm, 2006, 8, 189–201.
60. Wang, C.R.; Shi, Z.Q.; Lu, X.;Dunsch, L.; Wan, L.J.; Shu, C.Y.; Tang, Y.L. and Shinohara, H. C64H4: Production, Isolation and Structural Characterizations of the First Stable Unconventional Fulleride.J. Am. Chem. Soc. 2006, 128, 6605–6610.
61. Zeng, Q.D.; Wu, D.X.; Wang, C.; Lu, J.; Ma, B.C.; Shu, C.Y.; Ma, H.W.; Li, Y. and Bai, C.L. Bipyridine conformations control the solid-state supramolecular chemistry of zinc( II) phthalocyanine with bipyridines. CrystEngComm, 2005, 7(38), 243–248.
